WebThe monocytic cell line THP-1 can be stimulated to produce IFN-β when challenged with purified dsDNA oligomers > 80 bp, plasmids, bacterial DNA and human DNA. We have also … WebTHP1-Null cells are derived from THP-1 human monocytic cells, that represent the most commonly used model cell line for the study of inflammasome activation as they express …
Immobilized CRP precipitates FcγRI and FcγRII from radiolabeled ...
WebCaspase-4 knockout in THP-1 cells. Inflammasome activation in THP1-KO-CASP4 cells. Human caspase-4 (CASP4) and CASP5, and their murine ortholog CASP11 are a family of inflammatory caspases that play a crucial role in the non-canonical inflammasome responses to intracellular lipopolysaccharide (LPS) [1-3]. More details InvivoGen has … WebApr 14, 2024 · Escartín-Gutiérrez JR, Ponce-Figueroa M, Torres-Vega MÁ, Aguilar-Faisal L, Figueroa-Arredondo P. Transcriptional Activation of a Pro-Inflammatory Response (NF-κB, AP-1, IL-1β) by the Vibrio cholerae Cytotoxin (VCC) Monomer through the MAPK Signaling Pathway in the THP-1 Human Macrophage Cell Line. limits and fits calculator imperial
Differential susceptibility to lipopolysaccharide affects the ...
WebWnt5a activated THP-1 cells, enhancing adhesion to endothelial cells. Hypoxia induced the production of Wnt5a, suggesting a role in the hypoxia-induced activation of macrophages. Wnt5a induced the expression of various pro-inflammatory cytokines and inflammatory mediators, particularly IL8 and CXCL2, suggesting a major role in the secretion of CXC … WebWe previously established an in vitro test to identify contact and respiratory allergens based on interleukin-8 (IL-8) production in THP-1 cells. Here, we challenged it for identification of … WebTHP1-Blue™ were derived from the human THP-1 monocyte cell line by stable integration of an interferon regulatory factor (IRF)-inducible SEAP reporter construct. As a result, THP1-Blue™ ISG cells allow the monitoring of IRF activation by determining the activity of SEAP. The levels of IRF-induced SEAP in the cell culture supernatant are ... limits and fits online calculator