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WebMar 16, 2024 · Oral hydrocortisone may cause mild side effects such as weight gain, weakness, insomnia, mood swings, nausea, and increased risk of infection. However, … WebSteroids may have negative effects, particularly when used frequently or in large doses. Skin thinning, hyperpigmentation, acne, infections, cataracts, osteoporosis, and adrenal … WebApr 20, 2024 · Hydrocortisone cream is usually well-tolerated. But some of the more common side effects are itchy skin, skin irritation, and minor changes in skin color. … solscoffee