WebApr 12, 2024 · Completed prior therapy (including radiation and/or surgery) for CNS metastases ≥ 28 days prior to the start of the study and CNS tumor is clinically stable at the time of screening, and Participant is not receiving steroids and/or enzyme inducing anti-epileptic medications for brain metastases WebApr 2, 2024 · A maximum of three prior lines of systemic therapies for unresectable or metastatic melanoma are allowed. The last dose of prior therapy must have been received more than 4 weeks (for anti-PD-1, anti-PD-L1 or anti-CTLA-4) or more than 2 weeks (for V600BRAF or MEK inhibitor) prior to randomization.
DYP-688 by Novartis for Metastatic Uveal Melanoma: Likelihood …
WebTAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat people with a type of skin cancer called melanoma: that has spread to other parts of the body (metastatic) or cannot be removed by surgery (unresectable), and that has a certain type of abnormal “BRAF” (V600E or V600K mutation-positive) gene WebPhase III data showed median overall survival of 25.6 months in patients with BRAF+ V600E/K metastatic melanoma who received Tafinlar + Mekinist Tafinlar + Mekinist … greek open dance competition
Clinical Trial: Dato-DXd vs Chemotherapy in Inoperable, Metastatic …
WebDec 16, 2024 · As the first investigational therapy in a phase 3 trial to show a survival benefit in patients with the rare and potentially fatal metastatic uveal cancer, tebentafusp, a bispecific T-cell... WebMar 30, 2024 · Purpose: Up to 50% of patients with uveal melanoma (UM) develop metastatic disease with limited treatment options. The immunomodulating agent ipilimumab has shown an overall survival (OS) benefit in patients with cutaneous metastatic melanoma in two phase III trials. Web2 days ago · ClinicalTrials.gov. A study of Dato-DXd versus investigator’s choice chemotherapy in patients with locally recurrent inoperable or metastatic triple-negative … flower camping en france