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WebJul 1, 2013 · A multidomain, multifunctional 230-kDa extracellular matrix (ECM) protein, hensin, regulates the adaptation of rabbit kidney to metabolic acidosis by remodeling collecting duct intercalated cells. Conditional deletion of hensin in intercalated cells of the mouse kidney leads to distal renal tubular … Webglobal deletion of hensin resulted in early embryonic lethality at the time of appearance of the first columnar epithelium, visceral endoderm, supported this proposal. Hensin/DMBT1 hensin has been found to be deleted in a large number of epithelial malig-nancies, again supporting its role in epithelial differentiation (see ref. 10 for review). mark it read
Galectin-3 mediates oligomerization of secreted hensin using …
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