WebSep 29, 2024 · Daptomycin-Related Rhabdomyolysis Complicated by Severe Hyperkalemia and Acute Kidney Injury September 2024 DOI: 10.7759/cureus.29764 … WebDaptomycin requires prior approval. Baseline CK followed by weekly CK should be measured in patients placed on daptomycin due to increased risk of rhabdomyolysis. Increased dose of daptomycin may be indicated with documented MRSA bacteremia. Infections due to fungi, mycobacteria, or Actinomyces require longer durations of therapy –
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WebRhabdomyolysis has been reported in up to 5 percent of treated patients receiving daptomycin . Factors conferring increased risk for daptomycin-associated myopathy or … WebDaptomycin is reported to cause an elevation in creatine kinase levels, although frank rhabdomyolysis is rare. An even more infrequent occurrence is the simultaneous development of acute kidney injury and drug-induced liver injury with rhabdomyolysis. Daptomycin and rifampin combination are used for synergistic bactericidal action … incanedo
Daptomycin: Uses, Interactions, Mechanism of Action
WebConclusion: Daptomycin can be associated with elevations in CPK level and rhabdomyolysis despite reduction of dose. A baseline CPK level before starting … WebIntroduction: Daptomycin, macrolides, trimethoprim-sulfamethoxazole, linezolid, fluoroquinolones, and cefdinir are known to be associated with rhabdomyolysis. Other antibiotics may also lead to rhabdomyolysis, but no study has systemically compared rhabdomyolysis associations for many available antibiotics. WebJun 1, 2012 · Daptomycin is the first approved cyclic lipopeptide with bactericidal activity against Gram-positive bacteria [ 32 ]. Dosages above 8 mg/kg and an application interval … incandescent with our energies