Clinimacs prodigy specifications
WebCliniMACS® and MACS® GMP Products Amount required CliniMACS Prodigy with T Cell Transduction– Large Scale application software 1 CliniMACS CD4 and CD8 Reagent/GMP MicroBeads 1 piece each CliniMACS CD62L Reagent/GMP MicroBeads 1 piece CliniMACS Prodigy TS 620 1 piece CliniMACS PBS/EDTA Buffer (3 L) 1 piece … WebFeb 8, 2024 · The CliniMACS Prodigy® is such a platform that combines automation with processing in a single-use, closed-system tubing set. It supports automation of predefined processes, for instance T cell …
Clinimacs prodigy specifications
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Web17 rows · The CliniMACS Prodigy offers a flexible platform for cell processing applications enabling the ...
WebOct 1, 2024 · Upon installation of the closed, single-use tubing set on the CliniMACS Prodigy™, sterile welding of the starting cell product, and sterile connection of the required reagents, T cells are magnetically enriched, stimulated, transduced using lentiviral vectors, expanded, and formulated. WebAug 7, 2024 · We hypothesized that point of care manufacturing of CAR-T cells on the automated CliniMACS Prodigy® device allows reproducible and fast delivery of cells for the treatment of patients with non-Hodgkin lymphoma. Here we describe cell manufacturing results and characterize the phenotype and effector function of CAR-T cells used in a …
WebThe CliniMACS CD34 Reagent System is indicated for processing hematopoietic progenitor cells collected by apheresis (HPC, Apheresis) from an allogeneic, HLA-identical, sibling donor to obtain a... WebNov 5, 2024 · All PBMC vials for a given donor were thawed and pooled. Thawed PBMCs (0.93-1.17e8 cells) were loaded onto a CliniMACS Prodigy device, CD4 and CD8 T cells enriched by immunomagnetic sorting, and T cells placed in the culture chamber with IL-7, IL-15 and TransAct reagent to induce proliferation.
Web17 rows · The CliniMACS Prodigy represents the next generation in automated cell processing. This device ... CliniMACS Prodigy TCT is designed for CAR T cell manufacturing from whole …
WebApr 14, 2024 · This novel DNA vector system is based on an antibiotic-free nanovector technology ( 17, 18 ); it contains no immunogenic and components and comprises only clinically approved sequences. It is easy, simple, versatile, and cost-efficient to produce. lockwood place garage baltimoreWebThe CliniMACS Electroporator expands the possibilities of automated closed system cell processing. As a module of the CliniMACS Prodigy® … indigo leaves onlineWebMar 16, 2024 · This protocol describes the use of an automated cell processor and culture system, the CliniMACS Prodigy device sold by Miltenyi Biotec, for the local manufacture of CAR T-cells targeting the CD19 antigen. The manufacturing process will use a lentiviral vector (CAR19) provided by Lentigen, a wholly owned subsidiary of Miltenyi Biotec, to ... lockwood plumbingWebMar 20, 2024 · Abstract. Development of semi-automated devices that can reduce the hands-on time and standardize the production of clinical-grade CAR T-cells, such as … indigo legal softwareWebComparative schedules of the CD34 selection process with CliniMACS Plus and CliniMACS Prodigy. White, gray and black bars: column height depicts time, shading marks manual,... indigo lighting espace proWebAug 18, 2024 · The CD34+ enrichment program in the CliniMACS Prodigy software allows two different scales: normal (0.6 × 10 9 target cells/ 6 × 10 10 total cells) and large (1.2 × … indigo lighthouse germany gmbhWebCliniMACS Prodigy IQ/OQ Service includes the Installation and Operational Qualification (IQ/OQ) of the CliniMACS Prodigy to provide detailed, documented evidence according … indigo lighting ou 13931 notice montage